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1. The place of nicotinic acetylcholine receptor localization is:

1. effector cells of receiving cholinergic innervation

2. skeletal muscle cells

3. effector cells of receiving adrenergic innervation

4. neurons sympathetic and parasympathetic ganglia

5. carotid glomeruli

6. chromaffin cells of the adrenal glands

7. CNS neurons

2. The synthesis of acetylcholine involved:

1. Glucose

2. acetyl coenzyme A

3. choline

4. acetylcholinesterase

5. glycogen

3. Specify how the electrolyte balance of skeletal muscle cells during their depolarization;

1. increases the concentration of sodium ions in the cell

2. decreasing the concentration of potassium ions in the cell

3. The reduced concentration of sodium ions in the cell

4. increases the concentration of potassium ions in the cell

4. Specify the MN-holinomimetkki direct action:

1. pyridostigmine

2. proserine

3. demekary

4. bethanechol

5. aceclidine

6. carbacholine

7. galantamine

8. phosphacol

9. ekotiofat

5. Specify the MN-holinomimetiki with bright as M and N-effect:

1. physostigmine

2. proserine

3. pyridostigmine

4. pilocarpine

5. bethanechol

6. ambenony

7. galantamine

8. carbacholine

6. Galantamine has a direct effect on:

1. M-cholinergic receptors

2. N-cholinergic receptors

3. acetylcholinesterase

4. choline

7. The overall effects of carbachol and aceclidine are:

1. stimulation of the parasympathetic ganglia holinoretseptorov

2. stimulation of cholinergic receptors sympathetic ganglia

3. stimulation of intestinal motility

4. strengthening of salivation

5. mystical action

6. mydriatic effect

7. reduction of blood pressure

8. The increase in blood pressure

9. reduction of intraocular pressure

8. Specify the effect of lobeline on the breath:

1. deepens and quickens your breath

2. reduces the frequency and depth of breathing

3. increases pulmonary ventilation

4. reduces pulmonary ventilation

5. reflekgorno depresses the respiratory center

6. reflexively stimulates the respiratory center

9. Neostigmine on the background of atropine causes:

1. The reduction in blood pressure

2. The increase in blood pressure

3. increased intestinal motility

4. facilitating neuromuscular

5. The reduction in the tone of the skeletal muscles

10. Long-acting phosphacol explained by the fact that it:

1. The forms stable complex with acetylcholinesterase

2. is resistant to hydrolysis

3. irreversibly connected to holinoretseptorami

4. stimulates the synthesis of acetylcholine

5. inhibits the synthesis of acetylcholine

6. stimulates the synthesis of pseudocholinesterase

11. When intestinal atony can be used:

1. pilocarpine

2. demekary

3. izoflyurofat

4. proserine

5. carbacholine

6. bethanechol

7. edrophonium

12. Describe why for removing the effect of an overdose of muscle relaxants proserine competitive type of action should be used in combination with atropine:

1. for potentiating the action of neostigmine

2. to improve the tone of the skeletal muscles

3 to facilitate the passage of pulses in the synapses mioneyronalnyh

4. M to block effects

13. Specify antiglaukomatoznyh facility with a duration of up to 1-4 weeks:

1. proserine

2. pilocarpine

3. Meholah

4. demekary

5. ekotiofat

6. phosphacol

7. physostigmine

8. izoflyurofat

14. Identify the drug on the following grounds: the day used exclusively for treating glaucoma, has a mystical effect of up to 4 weeks:

15. Specify the location of M-anticholinergics action:

16. Platifillin lowers blood pressure, as it:

17. Note the effects of M-anticholinergics:

18. Evaluate the correctness of the assertion that atropine and scopolamine can have a therapeutic effect in Parkinson's disease:

19. tachycardia, dry mouth, and sedation is:

20. Enter the duration of scopolamine
21. Specify the substance used as midriatichesknh funds:

22. Describe how the blood pressure under the influence of carbachol administered on a background of atropine:

23. organophosphate poisoning, atropine is not ust¬ranyaet their effect on:

24. Specify the indications platifillina:

25. Specify the drug improves the peripheral circulation:

26. atropine poisoning is characterized by the following symptoms:

27. Identify the drug on the following grounds: causes mydriasis and paralysis of accommodation and intraocular pressure increases, the effect on the eye lasts up to 24 hours:

28. Specify the location ganglioblokiruyuschih action means:

29. Tubocurarine causes:

30. Ditilin hydrolyzed:

31. The effect of depolarizing muscle relaxants such as actions involving violations of electrolyte balance in the cells of skeletal muscle:

32. The longest muscle relaxant effect has

33. Specify the ganglioblokatorov on the cardiovascular system:

34. Describe how the effect of galantamine affect tubokurarina:

1. increases

2. weakens

3. does not affect

35. Specify the effect of Neostigmine introduced against the background of pentamine, the tone of the intestine:

1. increases

2. reduces

3. does not affect

36. Specify the drugs that can cause histamine liberatiou:

1. pentamin

2. gigrony

3. arfonad

4. ditilin

5. pancuronium

6. tubocurarine

7. pipekuroniyu

8. atracurium

37. For the short-term clinical procedures (intubation, reduction of dislocation, repositioning bone fragments, and others.) As appropriate to prescribe a muscle relaxant:

1. atracurium

2. tubocurarine

3. ditilin

4. melliktin

38. Specify measures to help an overdose of muscle relaxants competitive type of action:

1. CPR

2. The appointment of neostigmine

3. The introduction of neostigmine with atropine

4. transfusion of fresh blood

5. Appointment analeptikov

39. Identify the drug on the following grounds: lowers the tone of the skeletal muscles, the effect is lasting 6-8 hours, penetrate the BBB, is assigned inside:

1. tubocurarine

2. ditilin

3. pyrylium

4. melliktin

5. anatruksony

JOB ddya INDEPENDENT prescribing by topic: cholinergic agent

Write down:

1. Tool for Alzheimer's disease

2. The agent for induction of labor

3. Means with symptoms of overdose of muscle relaxants competitive type of action

4. Mydriatics to assign patients with glaucoma

5. The agent for the treatment of sea and air sickness

6. The means for sedation, modifying the reaction of the pupil to light

7. holinoliticheskoe agent used in conjunction with neostigmine methylsulfate to eliminate the competitive effects of overdose of muscle relaxants

8. The tool in the treatment of pulmonary edema short ¬deystviya

9. The agent for relaxation of skeletal muscles short-acting

Objective 1.

Patients suffering from glaucoma, within 6 months of use eyedrops to reduce intraocular pressure. As a result, applications of the drug achieved vnutriglazym pressure control, wherein no pain in the eye, as well as headaches and blurred vision. But along with positive action antiglaukomatoznyh patient developed an adverse reaction in the form of injection of vessels in the eye, irritation and swelling of the conjunctiva. Determine what drug was used the following set of patient medications - pilocarpine, aceclidine, Meholah, Neostigmine. Justify your choice.

Objective 2.

The patient, in a few years suffering angle-closure glaucoma, pilocarpine eye drops are used for applications in the eyes 3-4 times a day. There was a question of replacing the drug for longer duration of action reduces the frequency of administration to 1 time per week. What remedy is necessary to use for this patient? Justify the choice of drug.

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